Sociopaths/problem brains..

In listening to the current podcast with Brook about episode #233. She has said repeatedly that when we fight reality, we are believing our thoughts that ‘something has gone wrong in the world’.. but in this particular podcast when Brooke talks about sociopaths she stated that something ‘HAS gone wrong with their brains” … so, am i conflating two separate concepts? Are sociopaths the ‘wrong’ thing that has happened? Or is their inhumanity .. part of humanity, and nothing has gone wrong?